This is a 60 y.o. man with known esophageal squamous cell dysplasia for EGD surveillance. He is not a surgical candidate due to his multiple medical comorbidities, but is contemplating RF ablation therapy./nThis is an...
This is a 60 y.o. man with known esophageal squamous cell dysplasia for EGD surveillance. He is not a surgical candidate due to his multiple medical comorbidities, but is contemplating RF ablation therapy./nThis is an endoscopic example of the utility of using 1.2% Lugol's Iodine stain as a "negative-stain" for chromoendoscopy. Lugol's iodine stains to glycogen of the normal sqamous epithelium of the esophagus, whereas absence of staining (white areas) represent areas of glycogen depletion (dysplasia, neoplasia, Barrett's esophagus, are examples)./nThis patient had confirmed squamous cell high grade dysplasia in biopsies taken from the unstained light areas, and normal squamous mucosa in the intervening brown stained regions.
(The visible mucosal "lesions" seen at 0:18-0:26 seconds were mucus and debris which washed away)